Unveiling the role of RARs in stomach adenocarcinoma: clinical implications and prognostic biomarkers.

ABSTRACT:

Background

Retinoic acid receptors (RARs) family are known to play a significant role in the occurrence and development of tumors. However, the relationship between RARs and stomach adenocarcinoma (STAD) has not yet been clearly identified. The aim of this study is to evaluate the expression profile and clinical value of the RARs family in STAD.

Methods

The expression level, clinical characteristics, prognostic value, immunity-related evaluations, genetic alteration and methylation site of RARs in STAD were explored using a series of online databases including gene expression profiling interactive analysis (GEPIA), tumor immune estimation resource (TIMER), University of Alabama at Birmingham cancer data (UALCAN), Human Protein Atlas (HPA), Kaplan-Meier plotter, gene set canc

SUBMITTER: Ren H 

PROVIDER: S-EPMC11384927 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature