Effect of Bimagrumab on body composition: a systematic review and meta-analysis.

ABSTRACT:

Background

Sarcopenia, a condition marked by progressive muscle mass and function decline, presents significant challenges in aging populations and those with chronic illnesses. Current standard treatments such as dietary interventions and exercise programs are often unsustainable. There is increasing interest in pharmacological interventions like bimagrumab, a monoclonal antibody that promotes muscle hypertrophy by inhibiting muscle atrophy ligands. Bimagrumab has shown effectiveness in various conditions, including sarcopenia.

Aim

The primary objective of this meta-analysis is to evaluate the impact of bimagrumab treatment on both physical performance and body composition among patients diagnosed with sarcopenia.

Materials and methods

This meta-analysis follows the

SUBMITTER: Kanbay M 

PROVIDER: S-EPMC11385021 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature