Non-invasive temporal interference brain stimulation reduces preference on morphine-induced conditioned place preference in rats.

ABSTRACT: Long-term use of opioid drugs such as morphine can induce addiction in the central nervous system through dysregulation of the reward system of the brain. Deep brain stimulation (DBS) is a non-pharmacological technique capable of attenuating behavioral responses associated with opioid drug consumption and possesses the capability to selectively activate and target localized brain regions with a high spatial resolution. However, long-term implantation of electrodes in brain tissue may limit the effectiveness of DBS due to changes in impedance, position, and shape of the tip of the stimulation electrode and the risk of infection of nerve tissue around the implanted electrode. The main objective of the current study is to evaluate the effect of temporal interference (TI) brain stimulation on

SUBMITTER: Mojiri Z 

PROVIDER: S-EPMC11385117 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature