A nomogram for overall survival of second primary cancers following upper-tract urothelial carcinoma: a SEER population-based study.

ABSTRACT:

Background

With improving prognosis in upper-tract urothelial carcinoma (UTUC), an increasing number of second primary malignancies (SPMs) are being identified. However, there is limited research on SPMs following UTUC. This study aims to evaluate the risk of SPMs in UTUC patients and create a nomogram to predict their survival rates.

Methods

Utilizing data from the Surveillance, Epidemiology, and End Results (SEER) database, we assessed the risk of SPMs among UTUC patients. Additionally, we developed and validated an overall survival (OS) nomogram for SPM patients post-UTUC diagnosis.

Results

The prevalence of SPMs among UTUC patients was 30.23%, with solid tumors being the most prevalent type of second malignancy, constituting 95.30% of all SPMs. The overall risk of

SUBMITTER: Zhang X 

PROVIDER: S-EPMC11385250 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature