Identifying developmental changes in functional brain connectivity associated with cognitive functioning in children and adolescents with ADHD.

ABSTRACT: Youth diagnosed with Attention-Deficit/Hyperactivity Disorder (ADHD) often show deficits in various measures of higher-level cognition, such as, executive functioning. Poorer cognitive functioning in children with ADHD has been associated with differences in functional connectivity across the brain. However, little is known about the developmental changes to the brain's functional properties linked to different cognitive abilities in this cohort. To characterize these changes, we analyzed fMRI data (ADHD = 373, NT = 106) collected while youth between the ages of 6 and 16 watched a short movie-clip. We applied machine learning models to identify patterns of network connectivity in response to movie-watching that differentially predict cognitive abilities in our cohort. Using out-of-sample c

SUBMITTER: Pho B 

PROVIDER: S-EPMC11385464 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature