Task-based functional neural correlates of social cognition across autism and schizophrenia spectrum disorders.

ABSTRACT:

Background

Autism and schizophrenia spectrum disorders (SSDs) both feature atypical social cognition. Despite evidence for comparable group-level performance in lower-level emotion processing and higher-level mentalizing, limited research has examined the neural basis of social cognition across these conditions. Our goal was to compare the neural correlates of social cognition in autism, SSDs, and typically developing controls (TDCs).

Methods

Data came from two harmonized studies in individuals diagnosed with autism or SSDs and TDCs (aged 16-35 years), including behavioral social cognitive metrics and two functional magnetic resonance imaging (fMRI) tasks: a social mirroring Imitate/Observe (ImObs) task and the Empathic Accuracy (EA) task. Group-level comparisons, and transd

SUBMITTER: Oliver LD 

PROVIDER: S-EPMC11385649 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature