A pan-cancer analysis of Wnt family member 7B in human cancers.

ABSTRACT:

Background

Previous studies have highlighted the crucial role of Wnt7B in the development of various cancers, including breast, pancreatic, and gastric cancers. However, research into the involvement of Wnt7B is often confined to specific tumor types, with a noticeable lack of comprehensive studies spanning multiple cancer forms. The potential of Wnt7B as a diagnostic or prognostic cancer biomarker has not been fully explored.

Methods

In this study, we combined bioinformatics and immunohistochemistry analyses to examine the expression patterns and functions of Wnt7B in cancerous and adjacent noncancerous tissues across a range of tumors.

Results

Our data indicate that Wnt7B may serve as a novel prognostic biomarker and therapeutic ta

SUBMITTER: Wang R 

PROVIDER: S-EPMC11386237 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature