White matter microstructure and functional connectivity in the brains of infants with Turner syndrome.

ABSTRACT: Turner syndrome, caused by complete or partial loss of an X-chromosome, is often accompanied by specific cognitive challenges. Magnetic resonance imaging studies of adults and children with Turner syndrome suggest these deficits reflect differences in anatomical and functional connectivity. However, no imaging studies have explored connectivity in infants with Turner syndrome. Consequently, it is unclear when in development connectivity differences emerge. To address this gap, we compared functional connectivity and white matter microstructure of 1-year-old infants with Turner syndrome to typically developing 1-year-old boys and girls. We examined functional connectivity between the right precentral gyrus and five regions that show reduced volume in 1-year old infants with Turner syndrome

SUBMITTER: Blanchett R 

PROVIDER: S-EPMC11387115 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature