Ultrasound based radiomics model for assessment of placental function in pregnancies with preeclampsia.

ABSTRACT: The goal of our research is to elucidate and better assess placental function in rats with preeclampsia through an innovative application of ultrasound-based radiomics. Using a rat model induced with L-NAME, we carefully investigated placental dysfunction via microstructural analysis and immunoprotein level assessment. Employing the Boruta feature selection method on ultrasound images facilitated the identification of crucial features, consequently enabling the development of a robust model for classifying placental dysfunction. Our study included 12 pregnant rats, and thorough placental evaluations were conducted on 160 fetal rats. Distinct alterations in placental microstructure and angiogenic factor expression were evident in rats with preeclampsia. Leveraging high-throughput mining of

SUBMITTER: Sun H 

PROVIDER: S-EPMC11387498 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature