High risk of misclassification of acute Parvovirus B19 infection into a systemic rheumatic disease.

ABSTRACT:

Objectives

Parvovirus B19 most frequently causes epidemics of erythema infectiosum in children but also affects adults often leading to rheumatologic manifestations. While the serum profile allows the diagnosis, manifestations may mimic autoimmune conditions. The aim was to evaluate the proportion of patients with acute Parvovirus B19 infection fulfilling classification criteria for rheumatic diseases (RA and SLE).

Methods

We evaluated the clinical and serological features of 54 patients diagnosed with acute Parvovirus B19 infection seeking rheumatological attention between March and June 2024.

Results

The majority of patients were females (78%), with a mean (s.d.) age of 45 (13) years and 54% could not recall any known exposure. Fifty-one/54 (94%) had arthralgia, 27

SUBMITTER: D'Onofrio B 

PROVIDER: S-EPMC11387767 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature