The value of PET/CT in the diagnosis and differential diagnosis of Parkinson's disease: a dual-tracer study.

ABSTRACT: Positron emission tomography/computed tomography (PET/CT) is a molecular imaging method commonly used to diagnose and differentiate Parkinson's disease (PD). This study aimed to evaluate the performance of PET/CT with ¹¹C-2β-Carbomethoxy-3β-(4-fluorophenyl) tropane (¹¹C-CFT) and ¹⁸F-fluorodeoxyglucose (¹⁸F-FDG) tracers in the differential diagnosis between PD, multiple system atrophy parkinsonian type (MSA-P), progressive supranuclear palsy (PSP) and vascular parkinsonism (VP) using the data of 220 patients with clinical PD-like symptoms. Of the 220 enrolled patients, 166 (PD, n = 80; MSA-P, n = 54; PSP, n = 15; VP, n = 17) completed the motor, cognitive and PET/CT assessment and were included in this study. ¹¹C-CFT and ¹⁸F-

SUBMITTER: Du X 

PROVIDER: S-EPMC11387816 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature