Birth Weight, Gestational Age, and Risk of Pediatric-Onset MASLD.

ABSTRACT:

Importance

Metabolic dysfunction-associated steatotic liver disease (MASLD) has become the most common chronic liver disease worldwide and is increasingly being diagnosed at younger ages, affecting more than one-third of young people with obesity.

Objective

To evaluate associations between perinatal conditions and risk of MASLD and associated progressive liver disease.

Design, setting, and participants

This nationwide, population-based case-control study included all biopsy-confirmed cases of MASLD in Sweden. Individuals aged 25 years or younger (hereafter, young individuals) with biopsy-proven MASLD between January 1, 1992, and December 31, 2016, were matched to up to 5 general population control individuals. Granular data on maternal and perinatal characteristics we

SUBMITTER: Ebrahimi F 

PROVIDER: S-EPMC11388034 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature