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Enhancing extraction efficiency of carpaine in Carica papaya L. leaves: coupling acid-base extraction with surfactant-assisted micro-flotation.


ABSTRACT: Carpaine, a major alkaloid in papaya leaves, has considerable cardiovascular benefits alongside its notable effects on muscle relaxation when utilized in medicine. In this study, the coupling of acid-base extraction and flotation was developed to completely remove the use of toxic solvents. This method entails the extraction of carpaine from Carica papaya L. leaves using hot water extraction alongside ultrasound-assisted extraction followed by the condensation of the species using surfactant-assisted flotation. The acid-base extraction was applied to alter the solubility of carpaine as desired at different stages of the process. The results showed that the carpaine extraction yield using all the treatments in conjunction was significantly higher compared to the control samples in wh

SUBMITTER: Lam TQ 

PROVIDER: S-EPMC11388190 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature