Impact of imaging features on selecting limited lymph node resection for cT1N0M0 lung cancer.

ABSTRACT:

Background

Controversy still exists in the medical community regarding the performance of limited mediastinal lymphadenectomy (LML) in early-stage lung cancer. The objective of this study was to identify predictors of mediastinal lymph node (mLN) status and analyze its role in guiding surgical strategy.

Methods

A retrospective cohort study was conducted on 2,834 surgical patients with peripheral cT1N0M0 non-small cell lung cancer between 2016 and 2018. Logistic regression was employed to identify predictors of N2 metastasis. Prognosis was compared between groups and independent prognostic factors were identified using Kaplan-Meier and multivariate Cox analysis.

Results

There were 2,126 patients with systematic mLN dissection and 708 with LML. The multivariate analysis

SUBMITTER: He H 

PROVIDER: S-EPMC11388245 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature