Intracranial metastasis of gastrointestinal stromal tumors: A literature review of published case reports and case presentation.

ABSTRACT:

Background

Intracranial metastasis of gastrointestinal stromal tumors (GISTs) is uncommon and the optimal management for these patients remains undefined. The introduction of selective tyrosine kinase inhibitors (TKI) has drastically improved survival in patients with GISTs. However, its efficacy in patients with intracranial metastasis of GISTs is uncertain due to poor penetration of the blood brain barrier. The role of surgery and radiotherapy in these patients has also not been established. No large-scale studies exist, and the literature is limited to case reports. We report a case treated at our institution, conducted a literature review of existing case reports, and discussed the optimal management of patients with intracranial metastasis of GISTs.

Methods

A literature

SUBMITTER: Lee ZD 

PROVIDER: S-EPMC11388333 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature