Post-Traumatic Stress Disorder and Risk of Degenerative Synucleinopathies: Systematic Review and Meta-Analysis.

ABSTRACT:

Objective

A systematic review was conducted to answer whether adult-onset post-traumatic stress disorder (PTSD) is associated with increased risk of Parkinson's disease (PD) and related synucleinopathies.

Design

A systematic search of Medline (Ovid), Embase (Elsevier), PsycInfo (Ovid), Cochrane Library (Wiley), and Web of Science (Clarivate) was performed using MeSH headings and equivalent terms for PTSD, PD, DLB, and related disorders.

Setting

No restrictions.

Participants

Eligible articles were published in peer-reviewed journals, sampled adult human populations, and treated PTSD and degenerative synucleinopathies as exposures and outcomes, respectively.

Measurements

Extracted data included diagnostic methods, sample characteristics, matching procedure

SUBMITTER: Jones MB 

PROVIDER: S-EPMC11388697 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature