Fungi-sensitized individuals have unique profiles where Alt a 1 dominates promoting response to grass, ragweed and cat allergens.

ABSTRACT:

Introduction

The aim of our work was to determine comprehensively the sensitization profile of patients hypersensitive to fungal allergenic components in the Ukrainian population, identifying features of their co-sensitization to allergens of other groups and establishing potential relationships between causative allergens and their ability to provoke this hypersensitivity.

Methods

A set of programs was developed using Python and R programming languages, implementing the K-means++ clustering method. Bayesian networks were constructed based on the created clusters, allowing for the assessment of the probabilistic interplay of allergen molecules in the sensitization process of patients.

Results and discussion

It was found that patients sensitive to fungi are polysensiti

SUBMITTER: Kalyniuk V 

PROVIDER: S-EPMC11388980 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature