Helicobacter pylori seropositivity associates with hyperglycemia, but not obesity, in Danish children and adolescents.

ABSTRACT:

Background

Helicobacter pylori colonizes the human stomach and may affect the inflammatory response, hormone production related to energy regulation, and gastrointestinal microbiota composition. Previous studies have explored a potential association between H. pylori infection and pediatric obesity with varying results. Considering the immunomodulatory effects of early-life infection with H. pylori that can confer beneficial effects, we hypothesized that we would find an inverse relationship between H. pylori seropositivity and obesity among Danish children and adolescents.

Methods

We assessed H. pylori seroprevalence in 713 subjects from an obesity clinic cohort and 990 subjects from a population-based cohort, aged 6 to 19 years, and examined its association with obesity an

SUBMITTER: Klove S 

PROVIDER: S-EPMC11389555 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature