A modified GLIM criteria-based nomogram for the survival prediction of gastric cancer patients undergoing surgical resection.

ABSTRACT:

Background

This study aimed to develop a comprehensive model based on five GLIM variables to predict the individual survival and provide more appropriate patient counseling.

Methods

This retrospective cohort study included 301 gastric cancer (GC) patients undergoing radical resection. C-reactive protein (CRP) as an inflammatory marker was included in GLIM criteria and a nomogram for predicting 5-year overall survival (OS) in GC patients was established. The Bootstrap repeated sampling for 1000 times was used for internal validation.

Results

Of the total 301 patients, 20 (6.64%) died within 5 years. CRP improved the sensitivity and accuracy of the survival prediction model (AUC = 0.782, 0.694 to 0.869 for the model without CRP; AUC = 0.880, 0.809 to 0.950 for the model

SUBMITTER: Luo X 

PROVIDER: S-EPMC11389597 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature