Factors driving norovirus transmission in long-term care facilities: A case-level analysis of 107 outbreaks.

ABSTRACT: Norovirus is the most common cause of gastroenteritis outbreaks in long-term care facilities (LTCFs) in the United States, causing a high burden of disease in both residents and staff. Understanding how case symptoms and characteristics contribute to norovirus transmission can lead to more informed outbreak control measures in LTCFs. We examined line lists for 107 norovirus outbreaks that took place in LTCFs in five U.S. states from 2015 to 2019. We estimated the individual effective reproduction number, R_i, to quantify individual case infectiousness and examined the contribution of vomiting, diarrhea, and being a resident (vs. staff) to case infectiousness. The associations between case characteristics and R_i were estimated using a multivariable, log-linear mixed mod

SUBMITTER: Chen Y 

PROVIDER: S-EPMC11389824 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature