A twin-driven analysis on early aging biomarkers and associations with sitting-time and physical activity.

ABSTRACT:

Background

Current physical activity guidelines may be insufficient to address health consequences in a world increasing in sedentary behavior. Physical activity is a key lifestyle factor to promote healthy aging, but few studies examine activity in conjunction with sitting. We examine how activity intensity and sitting behavior influence health and the extent to which physical activity might counter sitting.

Methods

We analyzed data from the Colorado Adoption/Twin Study of Lifespan behavioral development and cognitive aging (CATSLife) in adults aged 28-49 years (M = 33.16, SD = 4.93). We fit a linear mixed-effect model for body mass index (BMI) and total cholesterol/high-density lipoprotein ratio (TC/HDL). Leveraging the co-twin control approach, we explore the trade-off be

SUBMITTER: Bruellman R 

PROVIDER: S-EPMC11389938 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature