Investigation and quantification of composition variability in urinary stone analysis.

ABSTRACT:

Purpose

To investigate the variability in urinary stone composition analysis due to sampling and suggest potential solutions.

Materials and methods

We collected 1,135 stone fragments from 149 instances that had undergone a stone removal at Hanoi Medical University Hospital from January 2022 to August 2022. Each fragment was ground into fine powder and divided into separate specimens if the amount was abundant. For composition analyzing every specimen, Fourier transform infrared spectroscopy was performed. The composition of a given fragment was the average of its belonging specimens. The variability in composition was assessed on the fragment level (i.e., between fragments of an instance). We defined an instance as "significantly variable" if the maximum difference in any co

SUBMITTER: Le BD 

PROVIDER: S-EPMC11390264 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature