Brain morphometric changes in children born as small for gestational age without catch up growth.

ABSTRACT:

Introduction

Most infants born as small for gestational age (SGA) demonstrate catch up growth by 2-4 years, but some fail to do so. This failure is associated with several health risks, including neuropsychological development issues. However, data on the morphological characteristics of the brains of infants born as SGA without achieving catch up growth are lacking. This study aims to determine the structural aspects of the brains of children born as SGA without catch up growth.

Methods

We conducted voxel- and surface-based morphometric analyses of 1.5-T T1-weighted brain images scanned from eight infants born as SGA who could not achieve catch up growth by 3 years and sixteen individuals with idiopathic short stature (ISS) to exclude body size effects. Growth hormone (GH)

SUBMITTER: Takatani T 

PROVIDER: S-EPMC11390431 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature