Bleeding recurrence risk among hospitalized patients undergoing therapeutic plasma exchange: a multi-center study.

ABSTRACT:

Background

In hospitalized patients undergoing therapeutic plasma exchange (TPE), it is not known how TPE-associated bleeding risk is impacted by a prior bleeding episode. Therefore, to assess the prevalence and predictors of bleeding recurrence, we analyzed data from the Recipient Epidemiology and Donor Evaluation Study-III (REDS-III).

Materials and methods

Using a retrospective cross-sectional analysis of REDS-III public use files, we identified hospitalized adults who had a major bleeding episode prior to their first TPE procedure. Patients were classified into two cohorts based on bleeding recurrence (no-recurrence vs recurrence). After identifying potential predictors, we used multiple imputation by chained equations to impute variables with <30% missing data. Variable

SUBMITTER: Junior ASF 

PROVIDER: S-EPMC11390607 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature