The prognostic role of circulating tumor DNA across breast cancer molecular subtypes: A systematic review and meta-analysis.

ABSTRACT:

Objective

Circulating tumor DNA (ctDNA) is increasingly being used as a potential prognostic biomarker in cancer patients. We aimed to assess the prognostic value of ctDNA in different subtypes of breast cancer patients throughout the whole treatment cycle.

Materials and methods

PubMed, Web of Science, Embase, Cochrane Library, Scopus, and clinical trials.gov databases were searched from January 2016 to May 2022. The following search terms were used: ctDNA OR circulating tumor DNA AND breast cancer OR breast carcinoma. Only studies written in English were included. The following pre-specified criteria should be met for inclusion: (i) original articles, conference abstracts, etc.; (ii) patients with breast cancer; (iii) ctDNA measurement; and (iv) clinical outcome data such a

SUBMITTER: Guo N 

PROVIDER: S-EPMC11390625 | biostudies-literature | 2024 Jun

REPOSITORIES: biostudies-literature