Ex vivo electrical bioimpedance measurements and Cole modelling on the porcine colon and rectum.

ABSTRACT: Different pathological changes in the large intestine wall, associated with the development of different chronic diseases, including colorectal cancer, could be reflected in electrical bioimpedance readings. Thickness and composition of the mucus bilayer covering it in the luminal side, abundance of bacteria of the intestinal microbiota, the permeability of the epithelium and inflammation are some of these. However, scientific literature on electrical passive properties of the large intestine is scarce. In this study, complex impedance measurements at 8 frequencies were carried out on 6 specimens of porcine colorectal tissue, within half ab hour post-mortem, obtained from a local abattoir. For 5 different distances, measured proximally from the border of the anus, 3 readings were taken at

SUBMITTER: Jaimes-Morales SA 

PROVIDER: S-EPMC11391046 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature