Solid-State NMR ¹³C sensitivity at high magnetic field.

ABSTRACT: Sensitivity is the foundation of every NMR experiment, and the signal-to-noise ratio (SNR) should increase with static (B₀) magnetic field, by a proportionality that primarily depends on the design of the NMR probe and receiver. In the low B₀ field limit, where the coil geometry is much smaller than the wavelength of the NMR frequency, SNR can increase in proportion to B₀ to the power 7/4. For modern magic-angle spinning (MAS) probes, this approximation holds for rotor sizes up to 3.2 mm at 14.1 Tesla (T), corresponding to 600 MHz ¹H and 151 MHz ¹³C Larmor frequencies. To obtain the anticipated benefit of larger coils and/or higher B₀ fields requires a quantitative understanding of the contributions to SNR, utilizing standar

SUBMITTER: Han R 

PROVIDER: S-EPMC11391299 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature