The first outbreak of feline panleukopenia virus infection in captive Pallas's cats in Xining Wildlife Park.

ABSTRACT:

Introduction

In August 2021, an outbreak of Feline Panleukopenia Virus (FPV) was observed in four 3-month-old Pallas' cats at Xining Wildlife Park. Despite timely intervention, the Pallas'cat cubs continued to experience clinical symptoms including diarrhea, seizures, and decreased white blood cell count, and all four cats died.

Methods

FPV clinical suspicions were initially confirmed by positive Polymerase Chain Reaction (PCR) testing. Pathological and immunohistochemical examinations (IHC) were performed on some organs, and the results showed that, encephalitis, viral enteritis, and splenitis occurred.

Results

The virus replicates extensively in the cytoplasm of lymphocytes and macrophages in the lamina propria of the small intestine mucosa. A strain of FPV was succ

SUBMITTER: Wei J 

PROVIDER: S-EPMC11391486 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature