Comparison of the correlation of creatinine- and cystatin C-Based estimated GFR and their differences with new-onset heart failure in a community-based population with type 2 diabetes.

ABSTRACT:

Aims

This study aimed to investigate the impact of different estimated glomerular filtration rate (eGFR) values like cystatin C-based eGFR (eGFRcys), creatinine-based eGFR (eGFRcr), and their difference (eGFRdiff; eGFRcys -eGFRcr), on the incidence of heart failure (HF) in patients with type 2 diabetes(T2D).

Methods

Being a prospective cohort study, it included 7,967 patients with T2D who underwent serum creatinine and cystatin C tests as part of the Kailuan Group's 6th annual health examination (2016). Subsequently, eGFRcys, eGFRcr, and eGFRdiff were calculated. Patients were categorized into three groups: negative (<-15 mL/min/1.73 m²), midrange (-15 to 15 mL/min/1.73 m²), and positive (> 15 mL/min/1.73 m²) eGFRdiff groups, respectively. Fu

SUBMITTER: Sang D 

PROVIDER: S-EPMC11391673 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature