The role of esmolol in sepsis: a meta-analysis based on randomized controlled trials.

ABSTRACT:

Background

Sepsis is associated with a high incidence and mortality and poses a significant challenge to the treatment. Although esmolol has shown promise in sepsis treatment, its efficacy and safety remain contentious. This meta-analysis aims to clarify the role of esmolol in sepsis management.

Methods

PubMed, Embase, Web of Science, Cochrane library, clinicaltrials.gov and the Chinese Clinical Trial Registry were searched and references of relevant reviews and meta-analysis were also screened for appropriate studies. Keywords and free words of 'sepsis', 'esmolol' and 'randomized controlled trials' were used for search. Meta-analysis was performed using RevMan 5.3 software.

Results

Fifteen studies involving 1100 patients were included. Compared with the control group

SUBMITTER: Wei Y 

PROVIDER: S-EPMC11391746 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature