Bacterioruberin extract from Haloarchaea Haloferax marinum: Component identification, antioxidant activity and anti-atrophy effect in LPS-treated C2C12 myotubes.

ABSTRACT: Carotenoids are natural pigments utilized as colourants and antioxidants across food, pharmaceutical and cosmetic industries. They exist in carbon chain lengths of C₃₀, C₄₀, C₄₅ and C₅₀, with C₄₀ variants being the most common. Bacterioruberin (BR) and its derivatives are part of the less common C₅₀ carotenoid group, synthesized primarily by halophilic archaea. This study analysed the compositional characteristics of BR extract (BRE) isolated from 'Haloferax marinum' MBLA0078, a halophilic archaeon isolated from seawater near Yeoungheungdo Island in the Republic of Korea, and investigated its antioxidant activity and protective effect on lipopolysaccharide (LPS)-induced C2C12 myotube atrophy. The main components of BRE inclu

SUBMITTER: Lee H 

PROVIDER: S-EPMC11391814 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature