ECG Findings Are Poor Predictors for Adverse Events and Cardiac Death in Barth Syndrome.

ABSTRACT:

Background

Patients with Barth syndrome (BTHS) can present with cardiomyopathy. BTHS subjects are at risk for cardiac adverse outcomes throughout life, including malignant arrhythmias and death. Electrocardiogram (ECG) parameters have never been assessed as a tool to predict adverse outcomes in individuals with BTHS.

Objectives

The purpose of this study was to identify any ECG parameters including QRS fragmentation, presence of arrhythmia, or abnormal intervals that could predict adverse outcomes and cardiac death among the BTHS population.

Methods

We performed a retrospective case referent study on subjects with BTHS (n=43), and compared them with our reference group, subjects with idiopathic dilated cardiomyopathy (DCM) from a single institution (n=53) from 2007-202

SUBMITTER: Hutchinson A 

PROVIDER: S-EPMC11392022 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature