Whole-Brain Vascular Architecture Mapping Identifies Region-Specific Microvascular Profiles In Vivo.

ABSTRACT:

Background and purpose

The novel MR imaging technique of vascular architecture mapping allows in vivo characterization of local changes in cerebral microvasculature, but reference ranges for vascular architecture mapping parameters in healthy brain tissue are lacking, limiting its potential applicability as an MR imaging biomarker in clinical practice. We conducted whole-brain vascular architecture mapping in a large cohort to establish vascular architecture mapping parameter references ranges and identify region-specific cortical and subcortical microvascular profiles.

Materials and methods

This was a single-center examination of adult patients with unifocal, stable low-grade gliomas with multiband spin- and gradient-echo EPI sequence at 3T using parallel imaging. Voxelwise

SUBMITTER: Hohmann A 

PROVIDER: S-EPMC11392379 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature