<i>Streptococcus dysgalactiae</i> subsp. <i>equisimilis</i> infection and its intersection with <i>Streptococcus pyogenes</i>.

ABSTRACT: SUMMARYStreptococcus dysgalactiae subsp. equisimilis (SDSE) is an increasingly recognized cause of disease in humans. Disease manifestations range from non-invasive superficial skin and soft tissue infections to life-threatening streptococcal toxic shock syndrome and necrotizing fasciitis. Invasive disease is usually associated with co-morbidities, immunosuppression, and advancing age. The crude incidence of invasive disease approaches that of the closely related pathogen, Streptococcus pyogenes. Genomic epidemiology using whole-genome sequencing has revealed important insights into global SDSE population dynamics including emerging lineages and spread of anti-microbial resistance. It has also complemented observations of overlapping pathobiology between SDSE and S.

SUBMITTER: Xie O 

PROVIDER: S-EPMC11392527 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature