Frequency and distribution of eschar in patients with scrub typhus in India: systematic review of literature and meta-analysis.

ABSTRACT:

Introduction

Scrub typhus is a mite-borne tropical febrile illness with high mortality if untreated. The presence of eschar is pathognomonic, but a wide range of frequencies of eschar positivity has been reported in Indian patients. Therefore, this systematic review and meta-analysis aimed to ascertain the frequency (overall and geographic region-wise) and anatomical distribution of eschar in scrub typhus in India.

Methodology

We searched articles in two databases using: [(scrub OR typhus OR Orientia) AND (eschar) AND (India)]. The articles were independently screened and critically appraised by two authors. The frequency and distribution of eschar in patients with scrub typhus were pooled using a random-effect model.

Results

After the title-abstract and full-text scr

SUBMITTER: Gupta N 

PROVIDER: S-EPMC11392549 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature