Measurement of blood pressure in rats: Invasive or noninvasive methods?

ABSTRACT: Experiments should always be based on control values. This assumption fully applies to cardiovascular parameters, such as heart rate (HR) and blood pressure (BP), which are highly sensitive to various external and internal stimuli and can already be significantly altered when an experiment begins. Therefore, it is necessary to determine which values are defined as a starting point (i.e., control and baseline) or compare them with valid reference values if the goal is to evaluate the changes after experimental intervention. A generally accepted principle is a reciprocal relationship between BP and HR, in which one parameter affects the other and vice versa. BP can be measured using two methods-noninvasively (tail-cuff) and invasively (telemetry, direct measurements of BP after introducing t

SUBMITTER: Kapsdorferova V 

PROVIDER: S-EPMC11392657 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature