Biologicals for the treatment of lupus nephritis: a Bayesian network meta-regression analysis.

ABSTRACT:

Background

Previous studies comparing the efficacy and safety of different treatment regimens for lupus nephritis are scarce. Moreover, confounding factors such as the duration of follow-up were hardly adjusted in those studies, potentially compromising the results and their extents to clinical settings.

Objective

To rigorously investigate the efficacy and safety of biologics in patients with lupus nephritis using Bayesian network meta-regression analyses that adjust for the follow-up period, in order to provide more robust evidence for clinicians.

Methods

Databases comprising PubMed, Embase, MedlinePlus, Cochrane Library, Google Scholars, and Scopus were retrieved for eligible articles from inception to February 29, 2024. The primary endpoint was the complete respons

SUBMITTER: Liu X 

PROVIDER: S-EPMC11392858 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature