Characterization of the vaginal microbiota in Italian women with endometriosis: preliminary study.

ABSTRACT:

Purpose

This cross-sectional study aims to assess the interplay between the vaginal microbiota and endometriosis.

Methods

123 consecutive Italian fertile women, aged between 20 and 40 years old, were enrolled during a routine gynecological consultation; 24 were diagnosed with endometriosis and 99 did not complain of any gynecological disease. All women underwent a vaginal swab for the evaluation of the composition and diversity of vaginal microbiota by means of 16 s rDNA metagenomic sequencing.

Results

Compared to women with no gynecological disease, the vaginal microbiota in women with endometriosis showed a similar abundance of Lactobacillus spp.; however, a statistically significant lower abundance in the genera Pseudomonas (p < 0.01), Bifidobacterium (p < 0.05), N

SUBMITTER: Sessa R 

PROVIDER: S-EPMC11393154 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature