Surgery versus sclerotherapy versus combined therapy in head and neck lymphatic malformations in the pediatric population: systematic review and meta-analysis.

ABSTRACT:

Purpose

To systematically review current literature on the treatment of lymphatic malformations (LMs) of the head and neck to guide treatment strategy.

Methods and materials

A systematic review and meta-analysis of literature until 16 November 2021 was performed on treatments of LMs in the head and neck.

Results

Out of 9044 articles, 54 studies were eligible for inclusion with 26 studies providing detailed participant data. A total number of 1573 patients with a mean age of 21.22 months were analysed. Comparative meta-analysis did not reveal significant differences two proportions of volume reduction (≥ 50% and 100%) between sclerotherapy and surgical treatment. Regression demonstrated that positive predictors for volume reduction were surgery 17 (95% CI 0.26-34; p = 

SUBMITTER: Embrechts JLA 

PROVIDER: S-EPMC11393230 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature