Oculomic stratification of COVID-19 patients' intensive therapy unit admission status and mortality by retinal morphological findings.

ABSTRACT: To investigate if retinal thickness has predictive utility in COVID-19 outcomes by evaluating the statistical association between retinal thickness using OCT and of COVID-19-related mortality. Secondary outcomes included associations between retinal thickness and length of stay (LoS) in hospital. In this retrospective cohort study, OCT scans from 230 COVID-19 patients admitted to the Intensive Care Unit (ITU) were compared with age and gender-matched patients with pneumonia from before March 2020. Total retinal, GCL + IPL, and RNFL thicknesses were recorded, and analysed with systemic measures collected at the time of admission and mortality outcomes, using linear regression models, Pearson's R correlation, and Principal Component Analysis. Retinal thickness was significantly associated wi

SUBMITTER: Courtie E 

PROVIDER: S-EPMC11393335 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature