Pan-cancer analysis of m1A writer gene RRP8: implications for immune infiltration and prognosis in human cancers.

ABSTRACT:

Background

Ribosomal RNA Processing 8 (RRP8) is a gene associated with RNA modification and has been implicated in the development of several types of tumors in recent research. Nevertheless, the biological importance of RRP8 in pan-cancer has not yet been thoroughly and comprehensively investigated.

Methods

In this study, we conducted an analysis of various public databases to investigate the biological functions of RRP8. Our analysis included examining its correlation with pan-cancer prognosis, heterogeneity, stemness, immune checkpoint genes, and immune cell infiltration. Furthermore, we utilized the GDSC and CTRP databases to assess the sensitivity of RRP8 to small molecule drugs.

Results

Our findings indicate that RRP8 exhibits differential expression between tum

SUBMITTER: Huang Z 

PROVIDER: S-EPMC11393379 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature