Plant-based diet in hyperkalemic chronic kidney disease patients receiving sodium zirconium cyclosilicate: a feasibility clinical trial.

ABSTRACT:

Background

Plant-based diets (PBD) may induce hyperkalemia in chronic kidney disease (CKD) patients.

Objectives

We explored the safety and feasibility of PBD in hyperkalemic CKD patients receiving the potassium binder sodium zirconium cyclosilicate (SZC).

Methods

In the current 6-wk trial, 26 hyperkalemic patients with CKD stage 4-5 not on dialysis received a low-protein low-potassium diet plus SZC for 3 wk and then a PBD with high potassium content delivered as a weekly food basket while continuing SZC for subsequent 3 wk. Plasma potassium was monitored weekly and SZC was titrated to achieve normokalemia. The 24-h urine excretion of potassium and sodium, 24-h food records, dietary quality, nutritional status, Bristol stool scale, Quality of life (QoL), and renal trea

SUBMITTER: Avesani CM 

PROVIDER: S-EPMC11393394 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature