Estimating Adverse Events Associated With Herbal Medicines Using Pharmacovigilance Databases: Systematic Review and Meta-Analysis.

ABSTRACT:

Background

Herbal medicines (HMs) are extensively used by consumers/patients worldwide. However, their safety profiles are often poorly reported and characterized. Previous studies have documented adverse events (AEs) associated with HMs, such as hepatotoxicity, renal failure, and allergic reactions. However, the prevalence rate of AEs related to HMs has been reported to be low. To date, no systematic review and meta-analysis has comprehensively analyzed the AEs of HMs using published data acquired from pharmacovigilance (PV) databases.

Objective

This study aimed to (1) estimate the reporting rate of the AEs of HMs using PV databases and (2) assess the detailed data provided in AE reports.

Methods

In this systematic review and meta-analysis, MEDLINE/PubMed, SCOPUS, EM

SUBMITTER: Kongkaew C 

PROVIDER: S-EPMC11393504 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature