Challenges in Liver Transplantation for Hepatocellular Carcinoma: A Review of Current Controversies.

ABSTRACT: Liver transplantation (LT) remains one of the most effective treatments for hepatocellular carcinoma (HCC) and significantly enhances patient survival. However, the application of LT for HCC faces challenges owing to advancements in cancer-specific treatment modalities and the increased burden of patients' comorbidities. This narrative review explores current controversies and advancements in LT for HCC. Key areas of focus include the management of comorbidities and patient education by advanced practice nurses, impacts of frailty on waitlists and post-LT outcomes, selection criteria for LT in the era of new downstaging tools, role of radiology in patient selection, and implications of potential immunotherapy use both before and after LT. Additionally, the importance of immunosuppression m

SUBMITTER: Mauro E 

PROVIDER: S-EPMC11394545 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature