Transcriptomic Analyses to Unravel Cronobacter sakazakii Resistance Pathways.

ABSTRACT: The proliferation of antibiotic usage has precipitated the emergence of drug-resistant variants of bacteria, thereby augmenting their capacity to withstand pharmaceutical interventions. Among these variants, Cronobacter sakazakii (C. sakazakii), prevalent in powdered infant formula (PIF), poses a grave threat to the well-being of infants. Presently, global contamination by C. sakazakii is being observed. Consequently, research endeavors have been initiated to explore the strain's drug resistance capabilities, alterations in virulence levels, and resistance mechanisms. The primary objective of this study is to investigate the resistance mechanisms and virulence levels of C. sakazakii induced by five distinct antibiotics, while concurrently conducting transcriptom

SUBMITTER: Liu S 

PROVIDER: S-EPMC11394748 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature