Correlation of gut microbial diversity to sight-threatening diabetic retinopathy.

ABSTRACT:

Purpose

To determine the association of gut microbiome diversity and sight-threatening diabetic retinopathy (STDR) amongst patients with pre-existing diabetes.

Methods

A cross-sectional study was performed, wherein 54 participants selected in total were placed into cases cohort if diagnosed with STDR and those without STDR but had a diagnosis of diabetes mellitus of at least 10-year duration were taken as controls. Statistical analysis comparing the gut microbial alpha diversity between cases and control groups as well as patients differentiated based on previously hypothesized Bacteroidetes/Firmicutes(B/F) ratio with an optimal cut-off 1.05 to identify patients with STDR were performed.

Results

Comparing gut microbial alpha diversity did not show any difference betwe

SUBMITTER: Khan R 

PROVIDER: S-EPMC11395485 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature