Association between serum osmolality and deteriorating renal function in patients with acute myocardial infarction: analysis of the MIMIC- IV database.

ABSTRACT:

Background

To investigate the association between serum osmolality and deteriorating renal function in patients with acute myocardial infarction (AMI).

Methods

Three thousand eight hundred eighty-five AMI patients from the Medical Information Mart for Intensive Care IV were enrolled for this study. The primary outcome was deteriorating renal function. Secondary outcomes included the new-onset of acute kidney injury (AKI) and progress of AKI. < 293.2725 mmol/L was defined as low serum osmolality, and ≥ 293.2725 mmol/L as high serum osmolality based on upper quartile. Univariate and multivariate logistic regression models were used to explore the associations between serum osmolality and the development of deteriorating renal function, the new-onset of AKI and progress of AKI

SUBMITTER: Luo X 

PROVIDER: S-EPMC11395587 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature