MicroRNA profile of endometrial cancer from Indian patients-identification of potential biomarkers for prognosis.

ABSTRACT: Endometrial cancer is one of the major cancers in women throughout the world. If diagnosed early, these cancers are treatable and the prognosis is usually good. However, one major problem in treating endometrial cancer is accurate diagnosis and staging. Till date, the choice method for diagnosis and staging is histopathology. Although there are few molecular markers identified, they are not always sufficient in making accurate diagnosis and deciding on therapeutic strategy. As a result, very often patients are under treated or over treated. In this study, our group has profiled microRNAs from Indian patients using NGS-based approach. We have identified 212 differentially expressed microRNAs in endometrial cancer. Among these, there are 17 novel miRNAs. Since this data represents only India

SUBMITTER: Hegde S 

PROVIDER: S-EPMC11395764 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature