Conversion of Ultrasmall Glutathione-Coated Silver Nanoparticles during Dispersion in Water into Ultrasmall Silver Sulfide Nanoparticles.

ABSTRACT: Ultrasmall silver nanoparticles (2 nm) were prepared by reduction with sodium borohydride (NaBH₄) and stabilized by the ligand glutathione (a tripeptide: glycine-cysteine-glutamic acid). NMR spectroscopy and optical spectroscopy (UV and fluorescence) revealed that these particles initially consist of silver nanoparticles and fluorescing silver nanoclusters, both stabilized by glutathione. Over time, the silver nanoclusters disappear and only the silver nanoparticles remain. Furthermore, the capping ligand glutathione eliminates hydrogen sulfide (H₂S) from the central cysteine and is released from the nanoparticle surface as tripeptide glycine-dehydroalanine-glutamic acid. Hydrogen sulfide reacts with the silver core to form silver sulfide. After four weeks in dispersi

SUBMITTER: Wolff N 

PROVIDER: S-EPMC11397201 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature