Descriptives and genetic correlates of eating disorder diagnostic transitions and presumed remission in the Danish registry.

ABSTRACT:

Objective

Eating disorders (EDs) are serious psychiatric disorders with an estimated 3.3 million healthy life-years lost worldwide yearly. Understanding the course of illness, diagnostic transitions and remission, and their associated genetic correlates could inform both ED etiology and treatment. The authors investigated occurrences of ED transitions and presumed remission and their genetic correlates as captured by polygenic scores (PGSs) in a large Danish register-based cohort.

Methods

The sample compromised of 10,565 individuals with a diagnosis of anorexia nervosa (AN), bulimia nervosa (BN), or eating disorder not otherwise specified (EDNOS) with at least two registered hospital contacts between 1995 and 2018. Based on medical records, occurrence of diagnostic transitio

SUBMITTER: Abdulkadir M 

PROVIDER: S-EPMC11398592 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature